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Phys. Rev. E 78, 046304 (2008) [9 pages]

Multidirectional sorting modes in deterministic lateral displacement devices

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Brian R. Long1,3,*, Martin Heller2, Jason P. Beech3, Heiner Linke1, Henrik Bruus2, and Jonas O. Tegenfeldt3
1Materials Science Institute and Department of Physics, University of Oregon, Eugene, Oregon 97403-1274, USA
2Department of Micro- and Nanotechnology, Technical University of Denmark, DTU Nanotech Building 345 East, DK-2800 Kongens Lyngby, Denmark
3Department of Physics, Division of Solid State Physics and Nanometer Consortium, Lund University, S-22100 Lund, Sweden

Received 11 July 2008; published 2 October 2008

Deterministic lateral displacement (DLD) devices separate micrometer-scale particles in solution based on their size using a laminar microfluidic flow in an array of obstacles. We investigate array geometries with rational row-shift fractions in DLD devices by use of a simple model including both advection and diffusion. Our model predicts multidirectional sorting modes that could be experimentally tested in high-throughput DLD devices containing obstacles that are much smaller than the separation between obstacles.

© 2008 The American Physical Society

URL:
http://link.aps.org/doi/10.1103/PhysRevE.78.046304
DOI:
10.1103/PhysRevE.78.046304
PACS:
47.57.−s, 66.10.C−, 05.40.Jc, 47.61.−k

*Current address: Biomedicial Engineering Division, Oregon Health and Science University, 3303 S.W. Bond Ave., Portland, OR 97239.