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Phys. Rev. E 73, 011912 (2006) [7 pages]

Evolutionary origin of power-laws in a biochemical reaction network: Embedding the distribution of abundance into topology

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Chikara Furusawa1,2 and Kunihiko Kaneko3,2
1Department of Bioinformatics Engineering, Graduate School of Information Science and Technology, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan
2ERATO Complex Systems Biology Project, JST, 3-8-1 Komaba, Meguro-ku, Tokyo 153-8902, Japan
3Department of Pure and Applied Sciences, University of Tokyo, Komaba, Meguro-ku, Tokyo 153-8902, Japan

Received 21 February 2005; revised 1 September 2005; published 23 January 2006

The evolutionary origin of general statistics in a biochemical reaction network is studied here to explain the power-law distribution of reaction links and the power-law distribution of chemical abundance. Using cell models with catalytic reaction networks, we have confirmed that the power-law distribution for the abundance of chemicals emerges by the selection of cells with higher growth rates, as suggested in our previous study [ Phys. Rev. Lett. 90 088102 (2003)]. Through further evolution, this inhomogeneity in chemical abundance is shown to be embedded in the distribution of links, leading to the power-law distribution. We analyze the mechanism of this embedding and discuss the generality of the results.

© 2006 The American Physical Society

URL:
http://link.aps.org/doi/10.1103/PhysRevE.73.011912
DOI:
10.1103/PhysRevE.73.011912
PACS:
87.17.Aa, 87.23.Kg, 89.75.Hc