Phys. Rev. E 72, 051902 (2005) [5 pages]Dynamical model based on finite stacking enthalpies for homogeneous and inhomogeneous DNA thermal denaturationReceived 25 April 2005; revised 12 July 2005; published 1 November 2005 We present a nonlinear dynamical model for DNA thermal denaturation, which is based on the finite stacking enthalpies used in thermodynamical nearest-neighbor calculations. Within this model, the finiteness of stacking enthalpies is shown to be responsible for the sharpness of calculated melting curves. Transfer-integral and molecular dynamics calculations are performed to demonstrate that the proposed model leads to a good agreement with known experimental results for both homogeneous and inhomogeneous DNA. © 2005 The American Physical Society URL:
http://link.aps.org/doi/10.1103/PhysRevE.72.051902
DOI:
10.1103/PhysRevE.72.051902
PACS:
87.10.+e, 63.70.+h, 64.70.−p, 87.14.Gg
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